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Research

Our main research focus is on reproductive biology and medicine, particularly female and male fertility in livestock and other domestic animals. We are investigating a variety of basic physiological and also pathological reproductive processes: 

  • Recognition and establishment of pregnancy 

  • Embryo/gamete – maternal interactions and communication 

  • Extracellular vesicles/exosomes-mediated transfer of various molecular cargo as a new mechanism of embryo-maternal communication 

  • Identification of common and species-specific molecular mechanisms of endometrial receptivity and fertility 

  • Identification of biomarkers for female and male fertility/subfertility 

Research approaches: 

  • Analysis of temporal and spatial regulation of gene expression in the oviduct and the endometrium by RNA-seq approaches (spatial transcriptomics, low input RNA-seq, small ncRNA-Seq) 
  • Investigation of the RNA, protein, and metabolite cargo of extracellular vesicles/exosomes  

  • Role of microRNAs (miRNAs) in embryo-maternal communication and embryo development